才俊正青年
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雷和花 博士

 个人经历:

 1997.09 – 2001.06

 2002.02 – 2002.08

 2002.09 – 2005.06

 

 2005.09 – 2008.06

 

 2008.07 – 2011.04

 

 2011.05 – 2014.11

2014.12 -

 

中南民族大学化学系,生物化学专业,学士学位

海南双成药业有限公司药物合成实验室,实验员

中南民族大学化学与生命科学学院,分析化学专业,硕士学位

蛋白质及抗坏血酸的络合吸附波法测定

中国科学院水生生物研究所,水生生物学专业,博士学位

微囊藻毒素在鲫鱼和日本长耳兔中组织分布的比较研究

中国科学院武汉物理与数学研究所,博士后

兽药喹烯酮的毒理代谢组学研究

中国科学院武汉物理与数学研究所,助理研究员

中国科学院武汉物理与数学研究所,副研究员

研究方向:

毒理代谢组学研究;基于色谱-质谱联用的代谢组分析方法研究


代表性文章:

1. Xiu-Ju Zhao, Chongyang Huang, Hehua Lei, Xiu Nie, Huiru Tang, and Yulan Wang. Dynamic metabolic response of mice to acute mequindox exposure. Journal of Proteome Research, 2011, 10: 5183-5190.
2. Xuezhen Zhang, Ping Dapeng Li, Rong Tang, Hehua Lei, Yanyan Zhao. Time-dependent oxidative stress responses of crucian carp (Carassius auratus) to intraperitoneal injection of extracted microcystins. Bulletin of Environmental Contamination and Toxicology, 2009, 82: 574-578.
3. Hehua Lei, Ping Xie, Jun Chen, Gaodao Liang, Ming Dai, Xuezhen Zhang. Distribution of toxins in various tissues of crucian carp intraperitoneally injected with hepatotoxic microcystins. Environmental Toxicology and Chemistry, 2008, 27: 1167-1174.
4. Hehua Lei, Ping Xie, Jun Chen, Gaodao Liang, Ting Yu, Yan Jiang. Tissue distribution and depuration of the extracted hepatotoxic cyanotoxins microcystins in crucian carp (Carassius auratus) intraperitoneally injected at a sub-lethal dose. TheScientificWorldJournal, 2008, 8: 713-719.
5. Ming Dai, Ping Xie, Gaodao Liang, Jun Chen, Hehua Lei. Simultaneous determination of microcystin-LR and its glutathione conjugate in fish tissues by liquid chromatography-tandem mass spectrometry. Journal of Chromatography B 2008, 862: 43-50.
6. Xuezhen Zhang, Ping Xie,WeiminWang, Dapeng Li, Li Li, Rong Tang, Hehua Lei, Zechao Shi. Dose dependent effects of extracted microcystins on embryonic development, larval growth and histopathological changes of southern catfish. Toxicon, 2008, 51: 449-456.
7.  Jun Chen, Ping Xie, Dawen Zhang, Hehua Lei. In situ studies on the distribution patterns and dynamics of microcystins in a biomanipulation fish - bighead carp (Aristichthys nobilis). Environmental Pollution, 2007, 147: 150-157. 

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